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#DiseaseDetail#Swine Flu

Swine Influenza

What is Swine Influenza?

Swine influenza (swine flu) is a respiratory disease of pigs caused by type A influenza viruses that regularly cause outbreaks of influenza in pigs. Swine flu viruses can cause high levels of illness in swine herds, but usually, cause few deaths. Common signs in sick pigs include fever, depression, coughing (barking), discharge from the nose or eyes, sneezing, breathing difficulties, eye redness or inflammation, and going off feed. However, influenza-infected pigs also may not appear ill or be only mildly ill. Swine influenza viruses may circulate among swine throughout the year, but most outbreaks occur during the late fall and winter months similar to outbreaks of seasonal influenza in humans.

What is a variant influenza virus?

When an influenza virus that normally circulates in swine (but not people) is detected in a person, it is called a “variant influenza virus.” For example, if a swine influenza A H3N2 virus is detected in a person, that virus will be called an “H3N2 variant” virus or “H3N2v” virus.

Can humans be infected with swine influenza viruses?

Yes. Swine flu viruses do not normally infect humans, however, sporadic human infections with influenza viruses that normally infect swine have occurred. When this happens, these viruses are called “variant viruses.” Most commonly, human infections with variant viruses have occurred in people exposed to infected pigs. In addition, there have been documented cases of multiple persons becoming sick after exposure to one or more sick pigs. Also, cases of limited person-to-person spread of variant viruses have occurred.

Why are human infections with variant viruses of concern?

Influenza viruses that infect pigs may be different from human influenza viruses. Thus, influenza vaccines made against human influenza viruses are generally not expected to protect people from influenza viruses that normally circulate in pigs. In addition, because pigs are susceptible to avian, human and swine influenza viruses, they potentially may be infected with influenza viruses from different species at the same time. If this happens, it is possible for the genes of these viruses to mix and create a new virus. This type of major change in the influenza A viruses is known as antigenic shift. If this new virus causes illness in people and can be transmitted easily from person-to-person, an influenza pandemic can occur.

What symptoms do people have when they are infected with variant viruses?

People who have been infected with variant viruses have had symptoms similar to the symptoms of regular human seasonal influenza. These include fever, lethargy, lack of appetite and coughing. Some people also have reported runny nose, sore throat, eye irritation, nausea, vomiting and diarrhea.

How are variant influenza viruses spread?

Influenza viruses can be directly transmitted from pigs to people and from people to pigs. These infections have most commonly been reported after close proximity to infected pigs, such as in pig barns and livestock exhibits housing pigs at fairs. Infected pig cough or sneeze and droplets with influenza virus in them can spread through the air. If these droplets land in your nose or mouth, or are inhaled, you can be infected. There also is some evidence that you might get infected by touching a surface with the virus on it and then touching your mouth or nose. A third way to possibly get infected is to inhale droplets or dust containing influenza virus. Scientists aren’t really sure which of these ways of spread is the most common. Human-to-human transmission of variant flu viruses also has occurred, though this method of spread has been limited. This kind of transmission is thought to occur in the same way that seasonal flu transmits in people, which is mainly through coughing or sneezing by people who are infected. People also may become infected by touching something with flu viruses on it and then touching their mouth or nose. It’s important to note that in most cases, variant flu viruses have not shown the ability to spread easily and sustainably from person to person

How can human infections with variant influenza viruses be diagnosed?

To diagnose variant influenza A virus infection, a respiratory specimen would generally need to be collected within the first 4 to 5 days of illness (when an infected person is most likely to be shedding virus). However, some people, especially children, may shed virus longer. H1N1 pandemic, state health departments have the ability to test for novel (non-human) influenza viruses. However, if a variant influenza virus is suspected, it is sent for further testing.

What medications are available to treat variant flu infections in humans?

There are three different antiviral drugs that are recommended for the treatment of influenza: oseltamivir, peramivir and zanamivir.







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