Bernstein test (Acid perfusion test)

The Bernstein test is a method to reproduce symptoms of heartburn. It is most often done with other tests to measure esophageal function.

How is test performed?
The test is done in a gastroenterology laboratory. A nasogastric (NG) tube is passed through one side of your nose and into your esophagus. Mild hydrochloric acid will be sent down the tube, followed by salt water (saline) solution. This process may be repeated several times. You will be asked to tell the health care team about any pain or discomfort you have during the test.

How to prepare for the test?
You will be asked not to eat or drink anything for 8 hours before the test.

How will you feel during the test?
You may have a gagging feeling and some discomfort when the tube is put in place. The acid may cause symptoms of heartburn. Your throat may be sore after the test.

Why this test is performed?
The test tries to reproduce symptoms of gastroesophageal reflux (stomach acids coming back up into the esophagus). It is done to see if you have the condition.

How test results are interpreted?
Normal Results: The test results will be negative.
Abnormal Results: A positive test shows that your symptoms are caused by esophageal reflux of acid from the stomach.

Are there risks with this test?
There is a risk of gagging or vomiting