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Low Blood Pressure

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Overview
Low blood pressure might seem desirable, and for some people, it causes no problems. However, for many people, abnormally low blood pressure (hypotension) can cause dizziness and fainting. In severe cases, low blood pressure can be life-threatening.

A blood pressure reading lower than 90 millimeters of mercury (mm Hg) for the top number (systolic) or 60 mm Hg for the bottom number (diastolic) is generally considered low blood pressure.

The causes of low blood pressure can range from dehydration to serious medical or surgical disorders. It's important to find out what's causing your low blood pressure so that it can be treated.

Symptoms
For some people, low blood pressure signals an underlying problem, especially when it drops suddenly or is accompanied by signs and symptoms such as:

Dizziness or lightheadedness
Fainting (syncope)
Blurred vision
Nausea
Fatigue
Lack of concentration
Shock
Extreme hypotension can result in this life-threatening condition. Signs and symptoms include:

Confusion, especially in older people
Cold, clammy, pale skin
Rapid, shallow breathing
Weak and rapid pulse
When to see a doctor
If you have indications of shock, seek emergency medical help.

If you have consistently low blood pressure readings but feel fine, your doctor is likely just to monitor you during routine exams.

Even occasional dizziness or lightheadedness may be a relatively minor problem — the result of mild dehydration from too much time in the sun or a hot tub, for example. Still, it's important to see your doctor if you have signs or symptoms of hypotension because they can point to more serious problems. It can be helpful to keep a record of your symptoms, when they occur and what you're doing at the time.
Causes
Blood pressure is a measurement of the pressure in your arteries during the active and resting phases of each heartbeat.

Systolic pressure. The top number in a blood pressure reading is the amount of pressure your heart generates when pumping blood through your arteries to the rest of your body.
Diastolic pressure. The bottom number in a blood pressure reading refers to the amount of pressure in your arteries when your heart is at rest between beats.
Current guidelines identify normal blood pressure as lower than 120/80 mm Hg.

Throughout the day, blood pressure varies, depending on body position, breathing rhythm, stress level, physical condition, medications you take, what you eat and drink, and time of day. Blood pressure is usually lowest at night and rises sharply on waking.

Blood pressure: How low can you go?
What's considered low blood pressure for you may be normal for someone else. Most doctors consider blood pressure too low only if it causes symptoms.

Some experts define low blood pressure as readings lower than 90 mm Hg systolic or 60 mm Hg diastolic. If either number is below that, your pressure is lower than normal.

A sudden fall in blood pressure can be dangerous. A change of just 20 mm Hg — a drop from 110 systolic to 90 mm Hg systolic, for example — can cause dizziness and fainting when the brain fails to receive an adequate supply of blood. And big plunges, such as those caused by uncontrolled bleeding, severe infections or allergic reactions, can be life-threatening.

Conditions that can cause low blood pressure

Medical conditions that can cause low blood pressure include:

Pregnancy. Because the circulatory system expands rapidly during pregnancy, blood pressure is likely to drop. This is normal, and blood pressure usually returns to your pre-pregnancy level after you've given birth.
Heart problems. Some heart conditions that can lead to low blood pressure include extremely low heart rate (bradycardia), heart valve problems, heart attack, and heart failure.
Endocrine problems. Thyroid conditions such as parathyroid disease, adrenal insufficiency (Addison's disease), low blood sugar (hypoglycemia) and, in some cases, diabetes can trigger low blood pressure.
Dehydration. When your body loses more water than it takes in, it can cause weakness, dizziness, and fatigue. Fever, vomiting, severe diarrhea, overuse of diuretics and strenuous exercise can lead to dehydration.
Blood loss. Losing a lot of blood, such as from a major injury or internal bleeding, reduces the amount of blood in your body, leading to a severe drop in blood pressure.
Severe infection (septicemia). When an infection in the body enters the bloodstream, it can lead to a life-threatening drop in blood pressure called septic shock.
Severe allergic reaction (anaphylaxis). Common triggers of this severe and potentially life-threatening reaction include foods, certain medications, insect venoms and latex. Anaphylaxis can cause breathing problems, hives, itching, a swollen throat and a dangerous drop in blood pressure.
Lack of nutrients in your diet. A lack of the vitamins B-12 and folate can keep your body from producing enough red blood cells (anemia), causing low blood pressure.
Medications that can cause low blood pressure
Some medications can cause low blood pressure, including:

Water pills (diuretics), such as furosemide (Lasix) and hydrochlorothiazide (Maxzide, Microzide, others)
Alpha blockers, such as prazosin (Minipress)
Beta blockers, such as atenolol (Tenormin) and propranolol (Inderal, Innopran XL, others)
Drugs for Parkinson's disease, such as pramipexole (Mirapex) or those containing levodopa
Certain types of antidepressants (tricyclic antidepressants), including doxepin (Silenor) and imipramine (Tofranil)
Drugs for erectile dysfunction, including sildenafil (Revatio, Viagra) or tadalafil (Adcirca, Cialis), particularly when taken with the heart medication nitroglycerin
Types of low blood pressure
Doctors often break down low blood pressure (hypotension) into categories, depending on the causes and other factors. Some types of low blood pressure include:

Low blood pressure on standing up (orthostatic, or postural, hypotension). This is a sudden drop in blood pressure when you stand up from a sitting position or after lying down.

Gravity causes blood to pool in your legs when you stand. Ordinarily, your body compensates by increasing your heart rate and constricting blood vessels, thereby ensuring that enough blood returns to your brain.

But in people with orthostatic hypotension, this compensating mechanism fails and blood pressure falls, leading to dizziness, lightheadedness, blurred vision, and even fainting.

Orthostatic hypotension can occur for various reasons, including dehydration, prolonged bed rest, pregnancy, diabetes, heart problems, burns, excessive heat, large varicose veins, and certain neurological disorders.

A number of medications also can cause orthostatic hypotension, particularly drugs used to treat high blood pressure — diuretics, beta-blockers, calcium channel blockers, and angiotensin-converting enzyme (ACE) inhibitors — as well as antidepressants and drugs used to treat Parkinson's disease and erectile dysfunction.

Orthostatic hypotension is especially common in older adults, but it also affects young, otherwise healthy people who stand up suddenly after sitting with their legs crossed for long periods or after squatting for a time.

It's also possible to have delayed orthostatic hypotension, with signs and symptoms developing 5 to 10 minutes after a change in posture. This might be a milder form of the condition, or it could be an early stage of it.

Low blood pressure after eating (postprandial hypotension). This sudden drop in blood pressure after eating effects mostly older adults.

Blood flows to your digestive tract after you eat. Ordinarily, your body increases your heart rate and constricts certain blood vessels to help maintain normal blood pressure. But in some people these mechanisms fail, leading to dizziness, faintness, and falls.

Postprandial hypotension is more likely to affect people with high blood pressure or autonomic nervous system disorders such as Parkinson's disease.

Lowering the dose of blood pressure drugs and eating small, low-carbohydrate meals might help reduce symptoms.

Low blood pressure from faulty brain signals (neurally mediated hypotension). This disorder, which causes a blood pressure drop after standing for long periods, mostly affects young adults and children. It seems to occur because of a miscommunication between the heart and the brain.
Low blood pressure due to nervous system damage (multiple system atrophy with orthostatic hypotension). Also called Shy-Drager syndrome, this rare disorder causes progressive damage to the autonomic nervous system, which controls involuntary functions such as blood pressure, heart rate, breathing, and digestion. It's associated with having very high blood pressure while lying down.
Risk factors
Low blood pressure (hypotension) can occur in anyone, though certain types of low blood pressure are more common depending on your age or other factors:

Age. Drops in blood pressure on standing or after eating occur primarily in adults older than 65. Neurally mediated hypotension primarily affects children and younger adults.
Medications. People who take certain medications, for example, high blood pressure medications such as alpha-blockers, have a greater risk of low blood pressure.
Certain diseases. Parkinson's disease, diabetes, and some heart conditions put you at a greater risk of developing low blood pressure.
Complications
Even moderate forms of low blood pressure can cause dizziness, weakness, fainting and a risk of injury from falls.

And severely low blood pressure can deprive your body of enough oxygen to carry out its normal functions, leading to damage to your heart and brain.

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Egg White Component Lowers Blood Pressure

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A study by American scientists presented Wednesday supports the view that a substance in egg white has the ability to lower blood pressure without negative effects.Scientists reported that a component of egg whites, already popular as a substitute for whole eggs among health-conscious consumers concerned about cholesterol in the yolk may have another beneficial effect in reducing blood pressure, reports Science Daily.

Their study was part of the 245th National Meeting and Exposition of the American Chemical Society (ACS), the world's largest scientific society, which continues here through Thursday.

"Our research suggests that there may be another reason to call it 'the incredible, edible egg,'" said study leader Zhipeng Yu, Ph.D., of Jilin University.

"We have evidence from the laboratory that a substance in egg white -- it's a peptide, one of the building blocks of proteins -- reduces blood pressure about as much as a low dose of Captopril, a high-blood-pressure drug," Zhipeng Yu said.

Yu and colleagues, who are with Clemson University, used a peptide called RVPSL. Scientists previously discovered that the substance, like the family of medications that includes Captopril, Vasotec and Monopril, was an angiotensin-converting-enzyme (ACE) inhibitor.

It has a powerful ability to inhibit or block the action of ACE, a substance produced in the body that raises blood pressure.

The results of feeding the substance were positive, showing that RVPSL did not have apparent toxic effects and lowered blood pressure by amounts comparable to low doses of Captopril.

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